DNA is "read" from 3' to 5' end DNA and RNA are both written from 5' to 3' end Strands of nucleic acids run "anti-parallel" to each other
5' and 3' ends of DNA and RNA
If I have a DNA strand that consisted of the bases 3'-ATGGCTACT-5', what would the complementary RNA strand look like? Include the 5' and 3' ends.
Discuss causes, effects, and examples of point mutations
A point mutation occurs when a single nucleotide base in the genetic code is changed during DNA replication or transcription; results from substitution mutations Silent: a nucleotide changes, but the amino acid remains the same Missense: a nucleotide changes and so does the amino acid Nonsense: a nucleotide change results in a premature stop codon
Frameshift: insertion or deletion of a single nucleotide changes the "reading frame" of the DNA/mRNA
How are alleles and mutations related?
Missense mutation: Nonsense mutation:
Quick search: Find and share an example of a disorder caused by a frameshift mutation